Diagnostic accuracy of cytology for canine osteosarcoma compared to histopathology

PICO question
 What is the sensitivity and specificity of cytology as a test for canine osteosarcoma when compared to histopathology gold standard?
 
 Clinical bottom line
 Category research Diagnosis
 The number type study designs reviewed
 Overall, four diagnostic validity studies (two prospective two retrospective) were critically appraised
 Strength evidence
 Weak moderate
 Outcomes reported
 There evidence moderate strength support that highly sensitive specific diagnosing histologically confirmed osteosarcomas mesenchymal malignant neoplasms (cytological diagnosis sarcoma). Evidence weak suggests identifying exact histotype osteosarcoma) are low high, respectively. Finally, there currently indicating comparable preoperative after incisional biopsy osteosarcoma
 Conclusion
 Based on available evidence, accuracy in sarcomas whereas confident conclusion cannot be drawn regarding identification osteosarcoma). scant suggesting has (i.e. biopsy) osteosarcomas, however, more warranted confirm these results
 How apply this practice
 application into practice should take account multiple factors, not limited to: individual clinical expertise, patient’s circumstances owners’ values, country, location or clinic where you work, case front you, availability therapies resources.
 Knowledge Summaries resource help reinforce inform decision making. They do override responsibility judgement practitioner what best animal their care.